OneNote 2016 can be installed as an optional feature on the Office Installer. OneNote is absent from the suite as the Universal Windows Platform ( UWP) version of OneNote bundled with Windows 10 replaces it.

Office 2019 includes many of the features previously published via Office 365, along with improved inking features, LaTeX support in Word, new animation features in PowerPoint including the morph and zoom features, and new formulas and charts in Excel for data analysis. Unlike other versions of Microsoft Office, Office 2019 will only get two years of extended support, which means that support for Office 2019 will end on the same day as support for Office 2016 will, on October 14, 2025. Mainstream support for Office 2019 will end on October 10, 2023. Some features that had previously been restricted to Office 365 subscribers are available in this release. It was released to general availability for Windows 10 and for macOS on September 24, 2018. It is the successor to Office 2016 and was succeeded by Office 2021 on October 5, 2021. Microsoft Office 2019 is a version of Microsoft Office for both Windows and Mac.

Proofing only (11): Hausa, Igbo, isiXhosa, isiZulu, Kinyarwanda, Pashto, Romansh, Sesotho sa Leboa, Setswana, Wolof, Yoruba.

Partial (51): Afrikaans, Albanian, Amharic, Armenian, Assamese, Azerbaijani (Latin), Bangla (Bangladesh), Bangla (Bengali India), Basque (Basque), Belarusian, Bosnian (Latin), Catalan, Dari, Filipino, Galician, Georgian, Gujarati, Icelandic, Irish, Kannada, Khmer, KiSwahili, Konkani, Kyrgyz, Luxembourgish, Macedonian (Republic of Macedonia), Malayalam, Maltese, Maori, Marathi, Mongolian (Cyrillic), Nepali, Norwegian Nynorsk, Odia, Persian (Farsi), Punjabi (Gurmukhi), Quechua, Scottish Gaelic, Serbian (Cyrillic, Bosnia & Herzegovina), Serbian (Cyrillic, Serbia), Sindhi (Arabic), Sinhala, Tamil, Tatar (Cyrillic), Telugu, Turkmen (Latin), Urdu, Uyghur, Uzbek (Latin), Valencian, Welsh.

Full (40): English, Arabic, Bulgarian, Chinese (Simplified), Chinese (Traditional), Croatian, Czech, Danish, Dutch, Estonian, Finnish, French, German, Greek, Hebrew, Hindi, Hungarian, Indonesian, Italian, Japanese, Kazakh, Korean, Latvian, Lithuanian, Malay (Latin), Norwegian Bokmål, Polish, Portuguese (Brazil), Portuguese (Portugal), Romanian, Russian, Serbian (Latin, Serbia), Slovak, Slovenian, Spanish, Swedish, Thai, Turkish, Ukrainian, Vietnamese.

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